why science as we know it has come to an end

This is a pretty outrageous claim.

But this is my reasoning: science is a method of describing the world using precise methods. It began to take off properly when we had accurate rulers and clocks to measure things. This was how Gallileo separated what we now know as Newton's laws from Aristotle's earlier ideas that included friction in any result. We could only factor out the common sense idea of friction with accurate clocks and rulers. So accurate measuring lets us divide up the world and see things more clearly. But there comes a point when our measuring begins to suffer problems generated by itself. One is noise- at the very limits random noise interferes with the result. This can to some extent be factored away but eventually quantum noise sets in and we find we can't know with accuracy any result without interfering with it. So we rely on probability. Likewise, in outer space, we rely on models that interpret radiation to say what the universe is really like. And as you get further from earth the noise increases here too. 

Einstein with relativity and those who pioneered quantum mechanics have far less influence on our world than many imagine; they have a huge influence on telling us the limitations of our measuring though. And it is in measurment that the future of science resides. All else is just modelling and speculation. That will continue ad infinitum- becoming what I call fractal philosophy. Like the potentially infinite coast line of Norway with fjords on fjords, fractal philosophy can build theory on theory without every really increasing the useful length of the coastline or quantity of knowledge which is limited by the limits of measurement not theory.

Engineers and material scientists will continue to make astounding breakthroughs- as they always have- but we have reached the limits of academic science- it is now in a similar position to medieval scholastic philosophy aided by a university system that is a direct descendent of the monastery.

So, if you like making new things and seeing astounding stuff- quit science and take up engineering- preferably in a field that solves the problems caused by...engineering.